NICU application and impact of AOP transfusion guidelines based on PINT study

Ahmed, K (2017) NICU application and impact of AOP transfusion guidelines based on PINT study. Archives of Disease in Childhood, 102 (Sup. 1). ISSN 0003-9888 (Print) ; 1468-2044 (Online)

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Abstract/Book Review

Anaemia of prematurity is, in part, an exacerbation of the physiological anaemia of the newborn, combining a suppressed postnatal response to erythropoietin, increased blood Sampling, short RBC span in the newborn and the rapid increase in blood volume with growth. The rapid decline in haemoglobin concentration is most severe in infants of smaller gestational age Most neonatal blood transfusions are administered to maintain minimal, although ill-defined, levels of haemoglobin. Maintenance or ‘topup’ transfusions are triggered by haemoglobin thresholds, which have been compared during clinical trials. the largest trial made is (the Premature Infants in Need of Transfusion [PINT] study), Which concluded that the use of restrictive versus liberal transfusion practices does not appear to have a significant impact on the combined outcomes of mortality or major morbidities.

Item Type: Article
Uncontrolled Keywords: Anaemia, Infants
Subjects: Children, Young People and Developmental Pyschology > Babies
Department/People: Children, Young Adult and Family Services
Depositing User: Mr Mat Zaremba
Date Deposited: 02 Jun 2017 14:14
Last Modified: 02 Jun 2017 14:14

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